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Contrast-Enhanced Mammograms in St. Louis, Missouri

About Contrast-Enhanced Mammograms


What is a Contrast-Enhanced Mammogram?

A Contrast Enhanced Mammogram (CEM) is an advanced type of breast imaging that combines traditional mammography with an intravenous (IV) contrast agent. This contrast agent highlights areas of increased blood supply, which can be associated with certain types of breast abnormalities, including cancer. The result is a more detailed and informative image, especially helpful in detecting cancers that may not be visible on standard mammograms.

CEM is particularly useful for:

  • Evaluating suspicious areas found in regular mammograms

  • Screening in women with dense breast tissue

  • Monitoring known breast conditions

CEM may be recommended if you:

  • Have dense breast tissue, which can make abnormalities harder to detect with standard mammography

  • Have a high risk for breast cancer based on personal or family history

  • Need additional imaging after an abnormal screening mammogram or ultrasound

  • Are undergoing monitoring for previously diagnosed breast cancer or high-risk lesions

CEM is not typically recommended if you:

  • Have a known allergy to iodinated contrast material

  • Have impaired kidney function (discussed case-by-case)

  • Are pregnant or may be pregnant (alternative imaging may be suggested)

What to expect:

Before the exam:

  • A small IV line will be inserted into your arm to deliver the contrast agent.

  • You'll be asked questions about allergies, kidney function, and medical history.

During the exam:

  • The contrast dye is injected via the IV, usually iodine-based.

  • You will then undergo a mammogram, typically involving two sets of images per breast (low-energy and high-energy).

  • The entire process usually takes 20–30 minutes.

After the exam:

  • You can resume normal activities immediately.

  • The radiologist will analyze the images and send a report to your doctor.

CEM is well-tolerated, but some patients may experience mild discomfort or warmth during contrast injection.

Preparing for a Contrast Enhanced Mammogram: Do’s and Don’ts

 Do’s

  • Inform your doctor of any history of contrast allergies, kidney issues, or pregnancy.

  • Hydrate well the day before and after the exam to help flush the contrast material.

  • Take prescribed medications as usual, unless instructed otherwise by your provider.

  • Bring prior breast imaging records if done at another facility.

Don’ts

  • Don’t wear deodorant, lotions, or powders on your underarms or breasts on the day of the exam—they can interfere with the images.

  • Don’t eat heavily just before the exam if you are sensitive to IV contrast (not usually necessary, but ask your provider).

  • Don’t skip the appointment if you’re on your period—it’s safe to undergo CEM at any point in your cycle.

  • Don’t ignore signs of a contrast reaction (e.g., rash, itching, difficulty breathing). Seek medical attention if they occur after the exam.